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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRWD1 All Species: 11.82
Human Site: S2158 Identified Species: 26
UniProt: Q9NSI6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NSI6 NP_061836.2 2320 262920 S2158 P D T S S K S S D L G S V T E
Chimpanzee Pan troglodytes XP_001170924 2320 262999 S2158 P D T S S K S S D L G S V T E
Rhesus Macaque Macaca mulatta XP_001108655 2320 262912 S2158 P D T S S K S S D L G S V T E
Dog Lupus familis XP_544889 2401 270094 D2239 P D P G P K S D S E L V S V T
Cat Felis silvestris
Mouse Mus musculus Q921C3 2304 259007 V2150 K A S D L G S V T D S D V D C
Rat Rattus norvegicus XP_001054667 1799 202807 K1648 K F I Q T R P K R K L R R Q H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510724 2599 293992 S2179 E S E S M E A S E T A G S A K
Chicken Gallus gallus XP_416730 2299 260504 R2145 I R R A R N K R S R A P L K R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920441 2191 247687 E2037 R K H G G S S E S D A D S K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395863 1676 190205 S1525 R K T V P S V S A D S D S G E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201169 1837 210307 N1686 L R S G T D I N S N E G S E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.9 85.7 N.A. 78.7 44.7 N.A. 65.6 61.8 N.A. 44.7 N.A. N.A. 34.9 N.A. 27.3
Protein Similarity: 100 99.7 98.7 89.7 N.A. 86.1 57.7 N.A. 74.3 73.4 N.A. 61.4 N.A. N.A. 49.4 N.A. 42.3
P-Site Identity: 100 100 100 26.6 N.A. 13.3 0 N.A. 13.3 0 N.A. 6.6 N.A. N.A. 20 N.A. 0
P-Site Similarity: 100 100 100 26.6 N.A. 20 13.3 N.A. 40 13.3 N.A. 6.6 N.A. N.A. 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 0 10 0 10 0 28 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 37 0 10 0 10 0 10 28 28 0 28 0 10 0 % D
% Glu: 10 0 10 0 0 10 0 10 10 10 10 0 0 10 37 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 28 10 10 0 0 0 0 28 19 0 10 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 10 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 19 19 0 0 0 37 10 10 0 10 0 0 0 19 10 % K
% Leu: 10 0 0 0 10 0 0 0 0 28 19 0 10 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 10 0 10 0 0 0 0 0 % N
% Pro: 37 0 10 0 19 0 10 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 19 19 10 0 10 10 0 10 10 10 0 10 10 0 10 % R
% Ser: 0 10 19 37 28 19 55 46 37 0 19 28 46 0 19 % S
% Thr: 0 0 37 0 19 0 0 0 10 10 0 0 0 28 10 % T
% Val: 0 0 0 10 0 0 10 10 0 0 0 10 37 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _